Posted in RU486

Ru486: Give an Exit to Your Unplanned Pregnancy

She was a college student, living on her own in a big city. She was in a relationship with a boy for 4 years and he broke up with her after completing his graduation. Her life turned upside down when she found herself pregnant. She did not want a baby at that time, as her boyfriend left her few days ago. Beside this, she called her ex boyfriend about it and he did not take it so well. He suggested her to go for an abortion as he had a future ahead of him and he did not want to look back in his life. Moreover, she had great plans for her future so a child did not fit on her lifestyle. Therefore, she decided to go for an abortion. At the same time, she was very nervous because she was actually taking the life of a child. After making so many efforts, she finally went to her family doctor and the doctor prescribed her a medicine named RU486 for the termination of pregnancy.


RU486 is a renowned medication that is used by women for ending a pregnancy of 49 days or 7 weeks or less. RU486 possesses a generic drug known as Mifepristone that has anti progestational activity and indicated for the medical termination of intrauterine pregnancy through 49 days of pregnancy. It is also used in the treatment of hypercortisolism in patients with nonpituitary Cushing syndrome.

Mifepristone has anti-progesterone and antiglucocorticoid effects. It works by blocking the progesterone receptor and inhibiting the activity of progesterone, causing endometrial decidual degeneration. This results in softening and dilatation of cervical, the release of endogenous prostaglandins, and an increased sensitivity of the myometrium to the contractile effects of prostaglandins. This further decreases the production of Progesterone by the corpus luteum.

On the first day, a woman should take one tablet of Mifepristone 200 mg orally. On the second day, the woman should take four tablets of Misoprostol 200 mcg (800 mcg) orally or vaginally. You have to take a follow-up visit approximately 7 to 14 days after the administration of Mifepristone to confirm the complete termination of the pregnancy.

Some common side effects of RU486 include dizziness, nausea, diarrhea, vomiting headache, abdominal pain, back pain, sweating and indigestion.

Precautions while taking RU486:

If you are allergic or hypersensitive to Mifepristone, Misoprostol or any of the ingredients present in RU486 then do not use RU486. If you have a chronic adrenal failure, certain bleeding problems, porphyria, r undiagnosed growth in the abdomen, then you should not use RU486. If you are having a pregnancy outside the uterus or ectopic pregnancy, then do not use RU486. If you are a pregnant woman, planning to become pregnant or a lactating mother, then avoid using RU486. If you have a kidney disease, liver disease, lungs problem, breathing problems, anemia, or high blood pressure, then you should avoid using RU486. You should not consume grapefruit or grapefruit juice while taking RU486 as it may increase the risk of side effects of Mifepristone.

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